Important Safety Information for Wegovy® (Semaglutide)
Source: Wegovy® Prescribing Information, Novo
Nordisk
What is the most important information I should know about
Wegovy®?
Wegovy® may cause serious side effects, including:
- Possible thyroid tumors, including cancer. Tell your healthcare provider if you get a lump or swelling in your neck,
hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies
with rodents, Wegovy® and
medicines that work like Wegovy® caused thyroid tumors, including thyroid cancer. It is not known if
Wegovy® will cause thyroid
tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people
- Do not use Wegovy® if you or any of your family have
ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine
system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Do not use Wegovy® if:
- you or any of your family have ever had a type of
thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called
Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
- you have had a serious allergic reaction to
semaglutide or any of the ingredients in Wegovy®
Before using Wegovy®, tell your healthcare provider if you have any
other medical conditions, including if you:
- have or have had problems with your pancreas or
kidneys
- have type 2 diabetes and a history of diabetic
retinopathy
- have or have had depression, suicidal thoughts, or
mental health issues
- are scheduled to have surgery or other procedures that
use anesthesia or deep sleepiness (deep sedation)
- are pregnant or plan to become pregnant.
Wegovy® may harm your
unborn baby. You should stop using Wegovy® 2 months before you plan to become pregnant
- are breastfeeding or plan to breastfeed. It is not
known if Wegovy® passes
into your breast milk
Tell your healthcare provider about all the medicines you take,
including prescription and over-the-counter medicines, vitamins, and herbal supplements. Wegovy® may affect the way some medicines work
and some medicines may affect the way Wegovy® works. Tell your healthcare provider if you are taking other medicines to treat
diabetes, including sulfonylureas or insulin. Wegovy® slows stomach emptying and can affect medicines that need to pass through the stomach
quickly.
What are the possible side effects of Wegovy®?
Wegovy® may cause serious side effects, including:
- inflammation of your pancreas (pancreatitis). Stop using Wegovy® and call your healthcare provider right away if you have severe pain in your
stomach area (abdomen) that will not go away, with or without nausea or vomiting. Sometimes you may feel the
pain from your abdomen to your back
- gallbladder problems. Wegovy® may cause gallbladder problems, including gallstones. Some gallstones may need
surgery. Call your healthcare provider if you have symptoms, such as pain in your upper stomach (abdomen),
fever, yellowing of the skin or eyes (jaundice), or clay-colored stools
- increased risk of low blood sugar (hypoglycemia), especially those who also
take medicines for diabetes such as insulin or sulfonylureas. This
can be a serious side effect. Talk to your healthcare provider about how to recognize and treat low blood
sugar and check your blood sugar before you start and while you take Wegovy®. Signs and symptoms of low blood
sugar may include dizziness or light-headedness, blurred vision, anxiety, irritability or mood changes,
sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, or
feeling jittery
- dehydration leading to kidney problems. Diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may
cause kidney problems. It is important for you to drink fluids to help reduce your chance of dehydration.
Tell your healthcare provider right away if you have nausea, vomiting, or diarrhea that does not go
away
- severe stomach problems. Stomach
problems, sometimes severe, have been reported in people who use Wegovy®. Tell your healthcare provider if you
have stomach problems that are severe or will not go away
- serious allergic reactions. Stop
using Wegovy® and get
medical help right away, if you have any symptoms of a serious allergic reaction, including swelling of your
face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling
dizzy; or very rapid heartbeat
- change in vision in people with type 2 diabetes. Tell your healthcare provider if you have changes in vision during treatment with
Wegovy®
- increased heart rate.
Wegovy® can increase your
heart rate while you are at rest. Tell your healthcare provider if you feel your heart racing or pounding in
your chest and it lasts for several minutes
- depression or thoughts of suicide. You should pay attention to any mental changes, especially sudden changes in your
mood, behaviors, thoughts, or feelings. Call your healthcare provider right away if you have any mental
changes that are new, worse, or worry you
- food or liquid getting into the lungs during surgery or other procedures that
use anesthesia or deep sleepiness (deep sedation). Wegovy® may increase the chance of food getting into your lungs during surgery or other
procedures. Tell all your healthcare providers that you are taking Wegovy® before you are scheduled to have
surgery or other procedures
The most common side effects of Wegovy® may include: nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness
(fatigue), upset stomach, dizziness, feeling bloated, belching, low blood sugar in people with type 2 diabetes,
gas, stomach flu, heartburn, and runny nose or sore throat.
This information is provided for educational purposes only and is not a substitute
for professional medical advice. Always consult your doctor before starting or changing any medication.